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Guotai Junan's annual strategy for innovative drugs in 2025: innovative pharmaceutical companies have accelerated into the harvest period, and the valuation has been at a historical low in the past five years. Guotai Junan said that the centralized purchasing policy has become stable, mature and normalized, and the marginal impact has weakened. Innovative drugs have gained policy inclination in the medical insurance negotiation. In the past two years, the policy has continued to promote pharmaceutical innovation, and the top-level design and local supporting chain support the development of innovative drugs. Commercial insurance is expected to bring new growth momentum to China's pharmaceutical market, and the overall industry trend is upward. At present, the trend of innovative drug industry is improving, the supply continues to accelerate, and a number of domestic innovative drugs are approved soon, which is expected to drive a new round of heavy volume. At the same time, the commercialization has achieved remarkable results and has occupied a dominant position in some sub-sectors. Pharma's performance continued to differentiate, and innovative drugs and just-needed drugs performed well. Biotech commercialization continues to increase, per capita yield continues to increase, the node of turning losses is approaching, and innovation ushers in the harvest period. Horizontal comparison: compared with overseas peers, the overall valuation of domestic innovative pharmaceutical companies is in a historically low range; Vertical comparison: the valuation of SW- pharmaceutical biology and SW- chemical preparations is at a historical low in the past five years, and it is expected that the valuation of subsequent sectors will pick up.South Korea's exports increased by 12.4% and imports increased by 11.6% from December 1 to 10. South Korea's chip exports increased by 43% year-on-year from December 1 to 10.In addition to the front page content, today's People's Daily's main financial contents include: 1. Steady development of new quality productive forces-China Economic Observation in 2024 ③; 2. About 100 flying rainbow bridges built and under construction in China cross the blue ocean (new economic orientation); 3. VAT invoice data shows that the retail sales of household appliances increased by 74.4% in November. 4. The General Administration of Market Supervision regulates the whole process of business marketing behavior to prevent the waste of take-away catering; 5. China-Europe trains reach 227 cities in 25 countries in Europe, connecting more than 100 cities in 11 Asian countries, sending goods over 11 million TEUs and goods worth over 420 billion US dollars-crossing mountains and seas, and the "steel camel team" adds momentum to the world economy (building the "Belt and Road" and the first site); 6. Continue to play the role of the biggest engine of world economic growth (harmony); 7. Accelerate the arrival of "Digital Wisdom Future" (vertical and horizontal); 8. Continue to expand new consumption scenarios and new formats (everyone talks); 9. What do you think of the "China scenery" in the world economy (current economic question and answer in China)? 10. The two departments will further improve the working mechanism of centralized drug collection and implementation, and encourage the priority use of selected drugs and consumables; 11. Give full play to the role of bidding competition to help the standardized and healthy development of the bidding market (the way of governance); 12. The national economy is progressing steadily (number 2024); 13. Improve the quality and efficiency of life insurance management and do a good job in pension finance; 14. The global robot industry accelerates innovation and development (international perspective). In 2023, the number of newly installed industrial robots in China exceeded half of the world; 15. The active format of the new service consumption market characterized by digital and green is released to "new" vitality (consumption window, promoting the expansion and upgrading of service consumption); 16. Create more abundant new products for the integration of literature and tourism (market stroll); 17. CNCA issued an action plan to improve the quality management system certification of small and micro enterprises, improve product quality and increase quality supply (consumption kaleidoscope).

Details of the life of the murder suspect of UnitedHealth Insurance Company surfaced. On Tuesday, Luigi Mangione, the suspect accused of shooting a senior executive of United Health, had a brief struggle with police officers and shouted angrily when he was taken to a court in Pennsylvania. Man Ghioni, 26, turned to a group of reporters and shouted, "... completely unsociable, insulting the wisdom of the American people!" And then pushed away by the police. It is not clear what he is referring to. On Tuesday, more clues about his possible motive gradually surfaced. According to the police, Man Ghione had a handwritten declaration when he was arrested, which can let people know his mentality. According to The New York Times, an internal report of the new york police, after analyzing the document, concluded that Man Ghioni believed that killing was a proper response to what he thought was corruption in the medical industry. It is reported that Mann Ghioni wrote in the manifesto: "These parasites deserve it". According to Mancini's friends, his social media posts and other news reports, Mancini suffers from chronic back pain, which limits his daily life. His profile on X-ray shows an X-ray background picture with screws and steel plates inserted into his lower back.Details of the life of the murder suspect of UnitedHealth Insurance Company surfaced. On Tuesday, Luigi Mangione, the suspect accused of shooting a senior executive of United Health, had a brief struggle with police officers and shouted angrily when he was taken to a court in Pennsylvania. Man Ghioni, 26, turned to a group of reporters and shouted, "... completely unsociable, insulting the wisdom of the American people!" And then pushed away by the police. It is not clear what he is referring to. On Tuesday, more clues about his possible motive gradually surfaced. According to the police, Man Ghione had a handwritten declaration when he was arrested, which can let people know his mentality. According to The New York Times, an internal report of the new york police, after analyzing the document, concluded that Man Ghioni believed that killing was a proper response to what he thought was corruption in the medical industry. It is reported that Mann Ghioni wrote in the manifesto: "These parasites deserve it". According to Mancini's friends, his social media posts and other news reports, Mancini suffers from chronic back pain, which limits his daily life. His profile on X-ray shows an X-ray background picture with screws and steel plates inserted into his lower back.Syrian opposition forces claimed to have taken control of the eastern Syrian city of Deir ez-Zor. According to Al Jazeera and Arabiya TV, on the 10th local time, Hassan Abdel Ghani, commander of Syrian opposition forces, said that "the eastern Syrian city of Deir ez-Zor has been completely controlled".

The restricted shares with a market value of 463 million yuan were lifted today. Smith Barney, Foreign Service Holdings and Aimeike were among the top companies in terms of market value. On Wednesday (December 11th), the restricted shares of four companies were lifted, with a total lifting amount of 31.3389 million shares. According to the latest closing price, the total lifting market value was 463 million yuan. Judging from the amount of lifting the ban, one company lifted more than 10 million shares. Smith Barney Technology, Foreign Service Holdings and Pulitzer were among the top, with 24,446,500 shares, 6,503,200 shares and 234,800 shares respectively. Judging from the market value of lifting the ban, the number of shares lifted by a company exceeds 100 million yuan. Smith Barney Technology, Foreign Service Holdings and Aimeike are among the top companies in terms of market value, with market values of 392 million yuan, 34.8574 million yuan and 33.43 million yuan respectively. Judging from the proportion of shares released from the ban to the total share capital, the proportion of one company released from the ban exceeded 10%. Smith Barney Technology, Foreign Service Holdings and Aimeike are among the top companies, with the lifting rates of 29.38%, 0.28% and 0.05% respectively.Japan's producer price in November increased by 0.3% month-on-month, and it is estimated to increase by 0.2%. Japan's producer price in November increased by 3.7% year-on-year, and it is estimated to increase by 3.4%.Nippon Steel's share price rose by 1.2% shortly after the opening on Wednesday, and it is basically flat at present. In the news, US President Biden plans to formally prevent Nippon Steel from acquiring American steel companies for $14.1 billion. American steel stocks plunged overnight, once falling by 22%, and finally closed down by 9.7%.